I like it. It's simple to set up a basic database, I can change layouts without losing information, and it save me a gazillion hours of html coding.
I'm working on reference material for a game I play, and I have over 2500 entries. So far. I laid out the way I wanted each entry to look, saved the entire file as an html page and I'm in the process of simple 'C&P' each entry onto a new page. *lol* Sure, it's a lot of work, but it would have been a whole lot more work if I had to do everything by hand. I can even set up the individual appendices with FileMakerPro as well.
For the record, I have two other database programmes, Appleworks and the one that comes with MSOffice, and I haven't used them since I got FileMaker. Filemaker is far simpler to get started on.